WHAT IS DXM?
Dextromethorphan (DXM) is the active ingredient in most OTC cough medicines. Approved by the U.S. Food and Drug Administration in the 1950s, DXM is the most widely used cough suppressant ingredient in the United States. When taken according to labeling instructions, medicines that contain DXM are safe and effective. However, when taken in excessive amounts higher than recommended doses, DXM can produce dangerous side effects.
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WHERE IS DXM FOUND? (Buy Dextromethorphan)
It is in the morphinan class of medications with sedative, dissociative, and stimulant properties (at lower doses). Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. In its pure form, dextromethorphan occurs as a white powder.
Dextromethorphan is also used recreationally. When exceeding approved dosages, dextromethorphan acts as a dissociative hallucinogen. It has multiple mechanisms of action, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. Dextromethorphan and its major metabolite, dextrorphan, also block the NMDA receptor at high doses, which produces effects similar to other dissociative anesthetics such as ketamine, nitrous oxide, and phencyclidine. It was patented in 1949 and approved for medical use in 1953.
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